Basik® PDO Suture Cassettes

Overview

Polydioxanone (PDO) monofilament synthetic absorbable, sterile surgical suture is prepared from the polyester, poly(p-dioxanone).

Characteristics
Polydioxanone (PDO) exhibits

• Extended holding strength, maintains tensile strength for up to six weeks.                                                         
• Excellent handling, exceptional suppleness, and good knot security.
• Non-wicking, which eliminates bacterial migration along suture line.
• Violet color for better visibility during surgery.

Indications
Polydioxanone monofilament synthetic absorbable suture is indicated for use in soft tissue approximation, including use in pediatric cardiovascular and ophthalmic procedures. Polydioxanone suture is not indicated in adult cardiovascular tissue, microsurgery, and neural tissue. This suture is particularly useful when the combination of an absorbable suture and extended wound support (up to six weeks) is desirable.

Actions
PDO synthetic absorbable suture elicits a minimal acute inflammatory reaction in tissues, followed by gradual encapsulation of the suture by fibrous connective tissue. Progressive loss of tensile strength and eventual absorption of PDO sutures occurs by means of hydrolysis.

Tensile Strength
Subcutaneous tissue implantation studies in rats indicate PDO suture retains approximately 75% of initial tensile strength at 2 weeks, 65% at 4 weeks and 50% at 6 weeks post implantation.

Absorption
Absorption begins as a loss of tensile strength without appreciable loss of mass. Absorption of PDO sutures is minimal until about the 60th day after implant and is essentially complete within 6 months.

Compares to PDS®, Maxon®, Monodox® or Monoplus®.